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B-cells produce antibodies in response to instruction received from
A. Killer T-cells
B. Suppressor T-cells
C. Mast cells
D. Helper T-cells

Last updated date: 19th Jun 2024
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Hint:These cells are essential for almost all adaptive immune responses. They also help activate cytotoxic T cells to destroy infected target cells.

Complete Answer:
B cells are also named as B lymphocytes. These cells are a type of white blood cell subtype of the lymphocyte. They work by secreting antibodies in the humoral immune component of the adaptive immune system. In addition, B cells display antigens and secrete cytokines. In humans, B cells grow in the bone marrow. In birds, the B cells mature in the Fabricius bursa, a lymphoid organ where Chang and Glick were first found, and not from the bone marrow as generally thought.
T-cell or T-cell killer is a T-cell lymphocyte or a type of white blood cell that destroys cancer cells, infected cells or injured cells in other ways.
T-cell suppressor is a type of immune cell that inhibits the activity of certain other forms of lymphocytes to prevent the immune system from being overactive. Suppressor T cells are being examined in the treatment of cancer.
A mast cell is a connective tissue migrant cell that comprises several granules rich in heparin and histamine. Specifically, it is a form of granulocyte originated from myeloid stem cells that is a part of the neuroimmune and immune systems.
Helper T cells are perhaps the most important cells in the field of adaptive immunity, since they are necessary for almost all adaptive immune responses. Not only can they help enable B cells to secrete antibodies and macrophages to fight consumed bacteria, but they also help activate cytotoxic T cells to kill infected target cells.

Thus, the correct answer is option ‘D’. i.e., Helper T-cells.

Note:B lymphocytes work in the humoral immune portion of the adaptive immune system by secreting antibodies. B-cells bind to an antigen, obtain support from a cognate T cell and divide into a plasma cell that secretes significant quantities of antibodies.