Question

Assertion: HIV is called a retrovirus.
Reason: HIV can synthesize new genomic RNA on the RNA template itself without requiring a DNA intermediate.
A. Both Assertion and reason are correct and Reason is the correct explanation for Assertion.
B. Both Assertion and Reason are correct but reason is not the correct explanation for Assertion.
C. Assertion is correct but reason is incorrect
D. Both Assertion and Reason are incorrect.

Answer 1

Hint: The full form of HIV is the Human immunodeficiency virus infection. HIV infection is immunodeficiency syndrome is a disease caused by infection with the human immunodeficiency virus to the human immune system. i.e., HIV
HIV causes AIDS by destroying T4 cells. Hence, this weakens the immune system and allows opportunistic infections.

Complete answer:
-Both Assertion and Reason are correct and Reason is the correct explanation for Assertion: Reason is not correct so this option is not suitable for this question.
-Both Assertion and Reason are correct but the reason is not the correct explanation for Assertion: Reason is an incorrect explanation for the assertion. This option is not suitable for this question.
-Assertion is correct but the reason is incorrect: Infection of the host cell begins when the gp120 protein binds the CD4 and coreceptor. The virus is taken into the host cell by endocytosis. Elegant studies using membrane tracking dyes show that the virus uncoats from within the endocytic compartment as the viral envelope fuses with the endosome membrane, releasing the virion contents into the cytoplasm. Inside the infected host cell, the core protein remains associated with the RNA as it is copied into a single strand of DNA by the RNA-dependent polymerase activity of the reverse transcriptase enzyme.
The RNA is next degraded by another reverse transcriptase component, ribonuclease H, and the DNA
Strand is duplicated to form a double-stranded DNA copy of the original RNA genome. A complex of the double-stranded DNA and integrase enzyme moves into the nucleus. Then proviral DNA is integrated into the cell’s DNA through a complex sequence of reactions catalyzed by integrase. The integrated provirus can remain latent, giving no clinical sign of its presence. Alternatively, the provirus can force the cell to synthesize viral mRNA.
-Both Assertion and Reason are incorrect: Assertion is correct so this option is not suitable for this question.
So, the correct answer is “Option C”.

Note:
There is no specific medicine for HIV. There is a medicine which is used to stop the virus from multiplying antiretroviral Therapy is one of the major treatments for HIV / AIDS. Retrovirus is a member of a group of viruses. When the person is infected by HIV his immune system becomes too weak to fight any kind of infection or disease. When the person gets a severe infection it may cause death.