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An endogenous chemical agent of disease is
A) Uric acid
B) Protein deficiency
C) Vitamin deficiency
D) Pollutants

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Answer
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Hint: The agents or the substances that are released within the tissues, organs of the body are called endogenous chemical agents and these are produced by a metabolism, either as metabolic products or wastes, and if these substances may sometimes cause any damage or disease to the person.

Complete answer:
Generally we know that our bodies get sick because of diseases which are caused by some external factors, and chemical agents such as drugs, or any pollution that affect the body in many ways make it vulnerable to disease.
At the same time Every human body undergoes metabolism and so many metabolic products release in the body, and some of the products are reutilized or some stored in the body
Some of the endogenous substances and also the metabolic products that are released are enzymes, hormones and urea, uric acids, etc. And these endogenous substances along with mutations that occur in the body are called an intrinsic environment.
Vitamins, hormones, proteins all are even produced in the body also they do not produce any disease, but their deficiency may affect the body metabolism, the question is endogenous chemical agents that produce disease, so vitamin and protein deficiency are wrong options.
Pollutants are not endogenous substances, they are caused by the external environment so it is the wrong option.
Body produces some metabolic wastes everyday which include urea, uric acid, where they will be eliminated from the body, uric acid is daily eliminated by the kidney from the body, the uric acid accumulates in the joints to form the gout disease.

Option A is the correct answer.

Note: The substances produced in the body are called endogenous substances and their concentration in the body that cause disease so those metabolic substances are eliminated daily from the body through kidneys, one among that was uric acid if accumulated cause gout disease.