
ADA is an enzyme which is deficient in genetic discovery as SCID. What is the full form of ADA?
A.Adenosine deoxyaminase
B.Adenosine deaminase
C.Aspartate deaminase
D.Arginine deaminase
Answer
499.8k+ views
Hint: Gene therapy is useful for correcting a defective gene and manipulating the gene. For example, defective ADA genes can be replaced with good ones using gene therapy methods. ADA deficiency is an inherited disorder that damages the immune system and causes severe combined immunodeficiency that is SCID. People with SCID lack Virtually all immune protection from bacteria ,viruses and fungi.
Complete answer:
Gene therapy is the method of inserting DNA into an individual for the treatment of a disease. It is used to substitute a missing gene or to fix the mutant alleles. ADA is an inherited autosomal recessive condition that occurs as a result of producing defective or deficit adenosine deaminase (ADA). People who have the enzyme deficiency are affected with severe combined immunodeficiency that is SCID disorder. In the patient suffering from SCID functional ADA genes can be introduced ex-vivo as a trial of human gene therapy. In this method, a functional gene is firstly inserted into a retrovirus then it is introduced into isolated stem cells of the patient. This way ADA genes also get transferred and modified cells could be introduced again into the patients bone marrow.
Additional information: gene therapy elements a faulty gene or add a new gene in an attempt to cure disease or improve your body’s ability to fight infection or diseases. Gene therapy holds promise for treating a wide range of diseases like cancer ,heart diseases, diabetes and AIDS.
ADA is an enzyme which is deficient in the genetic disorder SCID. Due to the deletion of the gene coding for adenosine deaminase (ADA) is caused.
Hence, the correct answer is option(B)
Note: In the above mentioned process, Lymphocytes are the cells that should be extracted from the patient's. After introduction of the modified Lymphocytes the gene becomes active and produces functional T-lymphocytes and the patient’s immune system also gets activated.
Complete answer:
Gene therapy is the method of inserting DNA into an individual for the treatment of a disease. It is used to substitute a missing gene or to fix the mutant alleles. ADA is an inherited autosomal recessive condition that occurs as a result of producing defective or deficit adenosine deaminase (ADA). People who have the enzyme deficiency are affected with severe combined immunodeficiency that is SCID disorder. In the patient suffering from SCID functional ADA genes can be introduced ex-vivo as a trial of human gene therapy. In this method, a functional gene is firstly inserted into a retrovirus then it is introduced into isolated stem cells of the patient. This way ADA genes also get transferred and modified cells could be introduced again into the patients bone marrow.
Additional information: gene therapy elements a faulty gene or add a new gene in an attempt to cure disease or improve your body’s ability to fight infection or diseases. Gene therapy holds promise for treating a wide range of diseases like cancer ,heart diseases, diabetes and AIDS.
ADA is an enzyme which is deficient in the genetic disorder SCID. Due to the deletion of the gene coding for adenosine deaminase (ADA) is caused.
Hence, the correct answer is option(B)
Note: In the above mentioned process, Lymphocytes are the cells that should be extracted from the patient's. After introduction of the modified Lymphocytes the gene becomes active and produces functional T-lymphocytes and the patient’s immune system also gets activated.
Recently Updated Pages
Master Class 12 Economics: Engaging Questions & Answers for Success

Master Class 12 Maths: Engaging Questions & Answers for Success

Master Class 12 Biology: Engaging Questions & Answers for Success

Master Class 12 Physics: Engaging Questions & Answers for Success

Master Class 12 Business Studies: Engaging Questions & Answers for Success

Master Class 12 English: Engaging Questions & Answers for Success

Trending doubts
What are saprophytes Give two examples class 12 biology CBSE

How do you convert from joules to electron volts class 12 physics CBSE

Mirage is a phenomena due to A Refraction of light class 12 physics CBSE

Why did French artist Frederic sorrieu prepare a series class 12 social science CBSE

What is Nutrition Explain Diff Type of Nutrition ?

Differentiate between microsporogenesis and megasporogenesis class 12 biology CBSE
