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Acrosome of sperm is derived from
A. Golgi vesicle
B. Lysosome
C. Nucleus
D. Cisternae

Answer
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Hint: The acrosome is a cap-like structure that covers almost the anterior half of the head in the sperm cells of many animals including humans. It contains digestive enzymes that are useful for breaking the outer membrane of the ovum thereby allowing the entry of the haploid nucleus of sperm into the ovum.

Complete answer:
Option (A) is correct. The acrosome of sperm is derived from the Golgi vesicle and contains certain digestive enzymes like hyaluronidase and acrosin that help in piercing the ovum.
Option (B) is incorrect. The acrosome of sperm is not derived from the lysosome because the acrosome is a direct Golgi-derived secretory vesicle. The role of the lysosome is to break down excess or damaged cell parts and also destroys invading viruses and bacteria.
Option (C) is incorrect. The acrosome of sperm is not derived from the nucleus because the role of the nucleus is to contain the genetic information which is inherited from the parents to offspring. Sperm and egg contain a haploid nucleus that forms a diploid zygote after fertilization.
Option (D) is incorrect. Cisternae are flattened membrane vesicles of the Golgi bodies and endoplasmic reticulum that are known for packing and modifying proteins but do not form the acrosome of sperm. They also pack polysaccharides that are synthesized in the Golgi apparatus.

Hence, the correct answer is option (A).

Note: The acrosome of sperm is an acidic vacuole that is derived from Golgi vesicle and contains certain hydrolytic enzymes. In the case of globozoospermia i.e., a condition in which sperm has a round head, the Golgi apparatus is not transformed into the acrosome that leads to male infertility.