Question

What is an acromegaly? Name the hormone responsible for this disorder?

Answer 1

Hint: The anterior pituitary gland produces growth hormone. It is a lengthy single-chain polypeptide made up of \[191\] amino acids. It is produced in the anterior pituitary gland's somatotropic cells. The hormone is also stored and released by these cells. The growth hormone is in charge of regulating a number of physiological processes, including growth and metabolism. Animals and plants both use it as a medication.

Complete answer:
Part (i): Acromegaly is a hormonal disease characterized by the anterior lobe of the pituitary gland secreting too much growth hormone or somatotropin hormone after adolescence. Acromegaly is characterized by unusually enlarged bones of the lower jaw and limbs, as well as increased BMR, heartbeat, and excitement.
Part (ii): The pituitary gland's overproduction of Growth Hormone is the most common cause of this illness. The pituitary gland, also known as the Master Gland, is a tiny gland located near the base of the brain that synthesizes some of the body's most vital hormones. The surrounding nerve tissues and optic nerves are squeezed as a result of this gland's abnormal development.
Bone development and organ enlargement occur as a result of this. When compared to other people, persons with this condition have substantially bigger bones.
Few common symptoms are- Sleeplessness, Excess fatigue, A hoarse voice, Profuse sweating.
Frequent headaches, Abnormal weight gain, develop odour in the body, Enlargement of jaws or tongue, develops weakness in the muscles, painful and swollen joints, Excessive growth of hair in women, The fingers and toes are widespread.

Note:
Difference between gigantism and acromegaly- Gigantism is an uncommon illness caused by excessive growth hormone secretion in the body, which can develop throughout childhood or at any age prior to puberty. Acromegaly is a rare illness caused by the body's overproduction of growth hormone. It can strike at any age after puberty.