Question

Worn out RBCs are destroyed by
A. Kupffer cells
B. Bone cells
C. Mast cells
D. None of the above.

Answer 1

Hint: As red blood cells get older, they are destroyed through cells inside the spleen and lymph nodes. This takes place whether or not the red blood cell is broken or not. Red blood cells generally stay approximately three months earlier than being destroyed in this way.

Complete answer:
To answer this question, first, we need to know RBC’s (Red Blood Cell). Every second, two-three million RBCs are produced inside the bone marrow and eliminated into the circulation. Also called erythrocytes, RBCs are the maximum usual kind of cell determined within the blood, with every cubic millimeter of blood containing 4-6 million cells. RBCs are small enough to squeeze via the smallest blood vessels.
Now, let us find the solution from the option.
Kupffer cells, additionally called stellate macrophages are specialised macrophages positioned inside the liver lining the outer layers or walls of the sinusoids. They catch and damage and break down RBCs passing via the sinusoids. Red blood cells are damaged down through their phagocytic action, in which the hemoglobin molecule is split.
Bone is a mineralized connective tissue that reveals 4 sorts of cells- osteoblasts, bone lining cells, osteocytes, and osteoclasts. Bone exerts crucial features within the body, including locomotion, aid and safety of smooth tissues, calcium and phosphate storage, and harboring of bone marrow. So, bone cells are not involved in worn out RBCs.
Mast cellar is a tissue cell of the immune system of vertebrate animals. Mast cells mediate inflammatory responses including allergic reaction and allergic reactions. So, mast cells are not involved in worn out RBCs.

Hence, the correct answer is option (A)

Note: Old or broken RBCs are eliminated from the circulation through macrophages within the spleen and liver, and the hemoglobin they comprise is damaged down into heme and globin. The globin protein can be recycled, or damaged down similarly to its constituent amino acids, which can be recycled or metabolized.