Question

Which of the following is related to glycosylation of protein?
(a)Endoplasmic Reticulum
(b)Peroxisome
(c)Lysosome
(d)Mitochondria

Answer 1

Hint Protein glycosylation occurs in an organelle that is composed of two subunits. The membranes are continuous with the outer nuclear membrane of this organelle. This organelle also participates in the folding of protein.

Complete answer:
The bonding of sugar residues to another organic compound is glycosylation. Glycoproteins are produced in the lumen of the rough endoplasmic reticulum but can subsequently be modified in the lumen of the Golgi apparatus, where other protein amino acids may become glycosylated.
Protein glycosylation is called the addition of a carbohydrate moiety to a protein molecule. It exists in the ER(Endoplasmic Reticulum) and in the cell body of the Golgi Apparatus.
Thus, the glycosylation of proteins requires the endoplasmic reticulum.

Additional information:
The endoplasmic reticulum is a continuous membrane system. It forms a series of flattened sacs inside the cytoplasm of eukaryotic cells. They have several multiple functions such as the synthesis, folding, modification and transport of proteins.
There are two subunits of the endoplasmic reticulum, such as the rough endoplasmic reticulum and the smooth endoplasmic reticulum. In most eukaryotic cells, the endoplasmic reticulum forms an interconnected network of flattened, membrane-enclosed sacs known as cisternae (in the rough endoplasmic reticulum) and in the smooth endoplasmic reticulum tubular structures. In red blood cells or spermatozoa, the endoplasmic reticulum is not present. In the creation of proteins, ribosomes are involved.
-Peroxisomes are involved in phospholipid production.
-In the oxidation of organic products, mitochondria are active.

So, the correct answer is, ‘Endoplasmic Reticulum’.

Note: The existence of a network or reticulum of tiny tubular structures dispersed in the cytoplasm called the endoplasmic reticulum is revealed by electron microscopic studies of eukaryotic cells.