Question

Which of the following diseases has a XXY chromosome constitution?
A. Down’s syndrome
B. Turner’s syndrome
C. Klinefelter’s Syndrome
D. Patau’s syndrome

Answer 1

Hint: A syndrome is a collection of symptoms and medical signs that are associated with each other and are frequently attributed to a serious illness or condition. If there is an extra chromosome, several chromosomal anomalies occur. Another happens when a portion of a chromosome is missing or duplicated.

Complete answer: Down syndrome is a genetic condition caused by the involvement of all or part of a third copy of chromosome 21, also known as trisomy 21. Turner syndrome occurs when one of the X chromosomes (sex chromosomes) is absent or partly missing, a disorder that affects only females.
Patau syndrome is a chromosomal abnormality-caused syndrome in which extra genetic information from chromosome 13 is borne by any or more of the body's cells.
Klinefelter syndrome is a genetic disorder in which an additional X chromosome is born to a boy. They have XXY rather than the usual XY chromosomes in males, so this disorder is often called XXY syndrome. Typically men with Klinefelter do not realize that they have it until they run into complications trying to have a child.
Klinefelter's syndrome is not inherited, but develops after conception only as a result of a rare mutation error. Low testosterone and decreased muscle mass, facial hair and body hair can be present in males born with Klinefelter's syndrome. The majority of men with this condition generate little to no sperm.
So, the correct answer is “Option C”.

Note:
60 percent of children with Klinefelter syndrome have been estimated to result in miscarriage. XXY males, as infants and children, can have weaker muscles and decreased strength. They begin to become taller than normal as they get older. They may have less power and coordination of their muscles than other boys of their age.