Question

Which of the following cells secretes cholecystokinin hormone?
A. Alpha cell
B. Beta cell
C. F cell
D. I cell

Answer 1

Hint: A peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein is known as cholecystokinin. Also called pancreozymin, the cholecystokinin is synthesized and secreted by the enteroendocrine cells in the duodenum, which is the first segment of the small intestine. The release of digestive enzymes and bile from pancreas and gallbladder are caused by its presence.

Complete answer:
Option A. Alpha cell: The endocrine cells in the pancreatic islets of pancreas are called the alpha cells. They make up to twenty percent of the human islet cells which synthesize and secretes the peptide hormone glucagon, and elevates the glucose levels in the blood. Since they do not secrete cholecystokinin hormone.
So, option A is not correct.
Option B. Beta cells: Cells that make insulin are called beta cells. Insulin is a hormone that controls the level of glucose in the blood. Within clusters of cells known as islets, the beta cells are found. Since beta cells do not secrete cholecystokinin hormone.
So, option B is also not correct.
Option C. F cell: The F cells or pancreatic polypeptide cells, also known as gamma cells, are cells in the pancreatic islets of pancreas. Pancreatic polypeptide is produced by them, on which they are named. They are polygonal in shape and are in few numbers. They are not responsible for the production of cholecystokinin.
Hence option C is also not correct.
Option D. I cell: Somatostatin, motilin, cholecystokinin, neurotensin, vasoactive intestinal peptide, and enteroglucagon are the hormones secreted by intestinal enteroendocrine cells. The I cell secrete cholecystokinin which are located in duodenum and jejunum. Bile secretion, exocrine pancreas secretion, and satiety are modulated by the I cell. Since cholecystokinin hormone is secreted by, I cell.
Option D is the correct answer.

Hence, Option D) I cell is the correct answer.

Note:
The cholecystokinin hormone plays an important physiological role both as a neuropeptide in the central nervous system and as a peptide hormone in the gut. This hormone participates in a number of processes like digestion, satiety and anxiety. The greatest stimulator of cholecystokinin release is the presence of fatty acids or certain types of amino acids in the chyme which enters the duodenum.