Question

What is the Stratum Granulosum?

Answer 1

Hint: Keratinized, stratified squamous epithelium makes up the epidermis. Depending on where it occurs in the body, it is made up of four or five layers of epithelial cells. It does not contain any blood vessels (i.e., it is avascular). The term "thin skin" refers to skin that has four layers of cells. The stratum basale, stratum corneum, stratum spinosum, and stratum granulosum are the layers that go from deep to shallow.

Complete answer:
Granular keratinocytes moved from the stratum spinosum to form this thin layer of the epidermis. The epidermis is made up of four or five layers in animals like vertebrates (each called stratum). These layers shield the skin's deeper layers from physical harm, infection, and water loss.
The epidermis in humans is made up of the following layers: (1) stratum corneum, (2) stratum lucidum, (3) stratum granulosum, (4) stratum spinosum, and (5) stratum basale or germinativum.
The Latin term stratum granulosum simply means "granular layer." This layer is situated between the stratum corneum (and, if present, the stratum lucidum) and the stratum spinosum. The stratum granulosum keratinocytes have an unique granular appearance. As a result, these keratinocytes are referred to as granular cells. They have keratohyalin granules in them, which help the keratin filaments stick together.
These cells also have lipid-filled lamellar bodies that are discharged into the extracellular environment via exocytosis. A lipid barrier is formed as a result of this. As they migrate from the stratum spinosum to the epidermis' top layers, these keratinocytes secrete them. When the cells reach the stratum corneum, they shed their nuclei and organelles and transform into corneocytes.

Note:-
The granular layer is hypothesised to receive, process, and delay input signals from a variety of modalities, including touch, vision, and balance, and then use these changed signals to generate responses that assist the body's muscles. A basal cell is a cuboidal-shaped stem cell that gives rise to epidermal keratinocytes.