Question

What increases CCK?

Answer 1

Hint: CCK stands for Cholecystokinin which is a peptide hormone. It is present in the gastrointestinal system and is responsible for stimulating the digestion of fats and proteins. It acts on both pancreases and gall bladder and stimulates their secretion of enzymes and juices.

Complete answer:
Cholecystokinin has been derived from the Greek language where chole, "bile"; cysto, "sac"; kinin, "move" or move the bile sac or gall- bladder. It is also called as pancreozymin that is secreted and synthesized by enter endocrine cells present in the duodenum which is the first segment of the small intestine. It helps in release of digestive enzymes and bile from the pancreas and gallbladder and also acts as a hunger suppressant.
Fats and proteins that are present in the stomach cause the release of cholecystokinin. Increased blood levels of cholecystokinin can be found after 15 minutes of the intake of the food and its level starts to begin and it remains raised till three hours afterwards. The release of this hormone can be blocked by somatostatin and by bile acids that are present in the small intestine.
CCK acts as an appetite suppressant and also helps in managing the weight of a person. Pancreatic enzymes released from the pancreases and bile juice from the small intestine flows through the duodenum and leads to digestion and absorption of very small molecules that stimulate cholecystokinin secretion. It increases in the body when there is excess of fats and protein taken in through food that needs to be digested. This causes an increase in the CCK level in the body.

Note:
The existence of CCK was first suggested by a British physiologist Joy Simcha Cohen in the year 1905 but it was discovered by Andrew Conway Ivy and Eric Oldberg. CCK is composed of various amino acids and it also exists in various forms, each identified by the number of amino acids it contains.