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Universal donor and universal acceptor is
A)O+ and AB-
B)O- and AB-
C)O+ and AB+
D)O- and AB+

Answer
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Hint: For an individual, the type of blood group is decided by the presence of antigen. Universal donors are those who can give their blood to any other blood group and universal acceptors are those who can accept blood from anyone.

Complete answer:
Let us first study the options to find the correct answer:

Option A: A, B, or Rh antigen are not present in the RBCs of O- which are safe for transfusion to any blood group and AB+ is the universal acceptors and the blood group type that do not have A, B antibodies. Therefore, they both are the universal donor and universal acceptor, and this the correct answer.

Option B: when there is no antigen present on RBC then the blood type is O with the antibodies A and B so O- and AB- are not the universal donor and universal acceptor. Therefore, this is an incorrect answer.

Option C: in AB+ there are both A and B antigens present but there is no antibody present on RBC. So, O+ and AB+ are not a universal donor and universal acceptor. Therefore, this is an incorrect answer.

Option D: as discussed above there is no antibody present on AB+ and no antigen present in blood type O so they are also not the universal donor and universal acceptor. Therefore, this is an incorrect answer.

Aside from the ABO blood grouping system, blood groups are additionally defined by the presence of the “Rh factor” on the membrane of RBCs. If the Rh factor is present, then the positive (+) sign is assigned to the ABO blood groups and in its absence the negative (-) sign is assigned.

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Hence, the correct answer is option (A)

Note: In the body of an organism, antigens are the molecules that are present on the surface of the cell and antibodies are the response on the immune system as they are the class of proteins that bind with the antigen.