Question

Universal donor and Universal acceptor is
a. O+ and AB-
b. O- and AB-
c. O+ and AB+
d. O- and AB+

Answer 1

Hint: Presence of antigen decides the type of blood group for an individual.

Complete answer:
1. O- their RBCs do not have any A, B or Rh antigens and are safe for the transfusion to any blood group. O- and AB+ are known as universal donors and universal acceptors.
2. AB+ blood group types are universal acceptors as they do not have A, B antibodies.
3. Antigens are the molecules that are present on the surface of the cell in the body of an organism.
4. These are considered a foreign particle when entering another organism’s body.
5. Antibodies, on the other hand, are the class of proteins that bind with antigens which is a response on the immune system.
6. On the basis of this antigen-antibody relation, humans have ABO and Rh blood grouping.
7. This was discovered by Karl Landsteiner in 1990 and AB blood group was reported by de Castello and Steini.
8. According to this if antigen present on RBC is A then its antibody is b the blood type is A and vice-versa.
9. When there is no antigen present on RBC the blood type is O with antibodies A and B.
10. When both antigens A and B are present on RBC, the blood type is AB and no antibody is found in plasma.
11. Another grouping is Rh grouping and if Rh antigen is present blood group is Rh positive and if absent it is Rh-negative.

For example: If a person has A antigen along with Rh antigen and B antibody the blood group is A+.

So, the correct answer is O- and AB+.

Note:
1. Human blood groups are the best example of codominance which is a deviation of Mendel’s Laws.
2. In codominance, the F1 generation resembles both parents.
3. In humans, they possess any two of the genes and when both the dominating genes are present they both express themselves.