Question

The hormone inhibin is produced by
A. Leydig cell
B. Sertoli cells
C. Graffian follicle
D. Corpus luteum

Answer 1

Hint: Inhibin hormone is involved in the negative feedback mechanism of gonadotropin hormone and this hormone is produced in males when the sperm count is low. It is produced by cells present in testes.

Complete answer:
> Option A is Leydig cell. Leydig cells are found in the seminiferous tubules of the testicle and it produces testosterone in the presence of luteinizing hormone. These cells express LH receptors and LH stimulates the leydig cells to produce androgen for the development of male reproductive tract and for the formation of sperms. The hormone inhibin is not produced by leydig cells and this is not the correct option.

> Option B is Sertoli cells. These are also found in testes and these cells secrete inhibin hormone which is involved in negative feedback mechanisms of the gonadotropin hormones. When the sperm count is low in males then inhibin hormone is produced by sertoli cells and it inhibits the secretion of FSH which is Follicle-stimulating hormone. Therefore, this is the correct option.

> Option C is graafian follicle. It is a fluid filled structure which is found in the ovary and from this graafian follicle, ovum develops before the process of ovulation. As asked in the question about the inhibin production, inhibin is not produced by graafian follicle since it is a part of ovary, it is produced by granulosa cells in ovary but it is not given in the options and Inhibin is produced by cells in the testes i.e., sertoli cells. Thus, this option is incorrect and it gets eliminated.

> Option D is Corpus luteum. Corpus luteum is a mass of cells which is found in the ovary and this functions for the production of the progesterone hormone not the inhibin hormone, inhibin hormone is not produced in ovary but it is produced by cells in the testes. Thus, this option is incorrect and it gets eliminated.

Hence, the correct answer is option (B).

Note: Sertoli cells are found in seminiferous tubules of testes and these cells are responsible for the production of inhibin hormone in order to inhibit the secretion of follicle stimulating hormone. This hormone is secreted by sertoli cells in the testes and by granulosa cells in the ovary and it is also synthesized by placenta.