Question

The enzyme DNA polymerase was discovered by:
A. Kornberg
B. Okazaki
C. Watson and Crick
D. Stahl and Meselson
E. Jacob and Monad

Answer 1

Hint: We have to remember that the identification and partial purification of the DNA polymerase I of Escherichia is done only in the year of 1956. It is the enzyme which catalyses the steady integration of deoxyribonucleotides into DNA in vitro originated as a surprise. It is the fact the most scientists in the field whispered that the DNA combination was too complex to be precisely reflected outside the living cell at that point of time.

Complete answer:
We must remember that the DNA polymerase is made purified and characterized from E. coli cells by a great scientist called Arthur Kornberg with help of his colleagues. It is said to be encoded by the polA gene. It is also known to catalyze phosphoryl group transfer. Therefore, the option A is correct.
We have to know that a DNA molecule present in the arrangement of a three-dimensional double helix. This is discovered by Watson and Crick. The experiments made by Stahl and Meselson showed that DNA simulated semi-conservatively. Therefore, the option C is incorrect.
We must remember that the way in which the lagging strand of DNA is replicated via fragments which are called as Okazaki fragments is discovered by the scientist Okazaki. Therefore, the option B is incorrect.
It is known that the specific proteins that are enthusiastic to repress the transcript of the DNA to its product, it is given by the experiments done by the scientists Jacob and Monad. Therefore, the option E is incorrect.
So, the correct answer is “Option A”.

Note:
We must remember that the 3-hydroxyl group of the nucleotide which present at the third end of the growing strand take the responsibility to serve as nucleophile for the attack of nucleophilic at the α phosphorus of the incoming deoxy nucleoside triphosphate. In this reaction, there is release of inorganic pyrophosphate.