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Source of somatostatin is the same as that of
A. Insulin and glucagon
B. Vasopressin and oxytocin
C. Thyroxine and calcitonin
D. Somatotropin and prolactin

Answer
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Hint: These hormones are secreted by the largest gland of the body. It plays an important role in the regulation of glucose in the body.

Complete answer: Growth hormone-inhibiting hormone (GHIH) is also called somatostatin. The regulation of the endocrine system and cell proliferation is the main function of somatostatin. In the digestive system mainly in the regions of the duodenum, pyrrolic antrum, and the pancreatic islets, the somatostatin is secreted by the beta cells of the pancreas whenever it is required by the body. The pyloric antrum is the position where somatostatin is released. From the portal venous system, it travels to the heart later entering into the systemic circulation of the body causing inhibitory effects. Also, somatostatin released from delta cells can act in a paracrine manner. Beta cells of the pancreatic islets produce peptide hormones called insulin and is mainly considered the main catabolic hormone in the body. Beta cells are sensitive to blood sugar levels so that they secrete insulin into the blood in response to a high level of glucose; inhibit the secretion of insulin when glucose levels are low. Glucose uptake and metabolism in the cells is enhanced by the insulin that reduces blood sugar levels in the body.
Hence, the correct answer is option A.

Note: Glucagon increases blood glucose levels by stimulating glycogenolysis and gluconeogenesis in the liver. The primary mechanism of glucose homeostasis is insulin and glucose secretion into the blood in response to the glucose concentration.