Question

Sertoli cells secrete a hormone
(A)Gonadotropin
(B)Testosterone
(C)Relaxin
(D)Inhibin

Answer 1

Hint: Sertoli cells produce and secrete the peptide hormone which is generally considered to play an endocrine role by inhibiting FSH-secretion from the pituitary. It is one of the two hormones secreted by the gonads.

Complete answer:
Sertoli cells secrete a hormone which is known as Inhibin. In humans, the hormone inhibin B-levels are high during the early postnatal life which then gradually declines but is still in a detectable plateau-level until puberty when the amount again increases. Measurements of inhibin B are clinically wont to assess the presence and performance of Sertoli cells during childhood.

Additional Information:
Sertoli cells help in the production of steroids and nutrients, together with an outsized number of proteins that will regulate reproductive cell growth and survival. These products secreted by Sertoli cells could also be secreted in a biphasic manner, i.e., either above the blood-testis barrier to act on haploid germ cells or below this barrier to influence cells located within the interstitium. Sertoli cells are also known as nurse cells, situated in the seminiferous tubules of the testis. Within the seminiferous tubules, these cells are interspersed with spermatogonia and extend from
the periphery of the tubules to the lumen. The function ranges from providing nutrition to providing
structural support to sperms. Sertoli cells support and nourish other cells. In the process of differentiation into the spermatozoa, most of the spermatid cytoplasm is discarded as residual bodies, which are phagocytosed by Sertoli cells.
So, the correct answer is ‘Inhibin’.

Note: FSH hormone checks the proliferation of the number of Sertoli cells within the seminiferous tubules. It also induces the Sertoli cells which are needed to release ABP( Androgen binding protein). FSH is a pituitary hormone discharged from the anterior pituitary gland. Testosterone is the hormone that is secreted by Leydig cells located between the seminiferous tubules.