Question

Release of pancreatic juice is stimulated by
(a)Enterokinase
(b)Secretin
(c)Trypsinogen
(d)Cholecystokinin

Answer 1

Hint: The pancreatic juice is an alkaline juice containing enzymes for the digestion of food by the exocrine portion of the pancreas. The release of pancreatic juice is stimulated by a hormone released by the small intestine.

Complete answer:
Cholecystokinin CCK is an enzyme released from the gastrointestinal tract of the small intestine and is responsible for the secretion of pancreatic juice and bile juice by stimulating the pancreas and gallbladder respectively. The pancreatic juice along with the bile juice opens into the duodenum region of the small intestine through the hepatopancreatic duct which is guarded by the sphincter of Oddi. The pancreatic juice contains inactive enzymes such as trypsinogen, chymotrypsinogen, procarboxypeptidase, amylases, lipases, and nucleases.

Additional Information: Let us look at the other terms given in the options.
Enterokinase: Enterokinase is an enzyme secreted by the mucosa layer of the small intestine which is responsible for converting inactive trypsinogen into active trypsin.
Secretin: Secretin is another hormone released from the gastrointestinal tract and is responsible for the secretion of water and bicarbonate ions by stimulating the exocrine part of the pancreas.
Trypsinogen: Trypsinogen is an enzyme of the pancreatic juice which is responsible for activating all the other enzymes of that juice once it is activated.
So, the correct option is ‘Cholecystokinin’.

Note: -The bile juice released from the gallbladder does not contain any enzymes. It has bile salts in it which are responsible for the emulsification of fats.
-Along with pancreatic and bile juice, another juice is released at the duodenum known as the intestinal juice or succus entericus.
-Succus entericus is made up of secretions from the brush border epithelium cells of the small intestine and goblet cells.