Question

Prothrombin, albumin and fibrinogen are synthesised by
A. Pancreas
B. Bone marrow
C. Spleen
D. Liver

Answer 1

Hint:This organ plays a central role in all metabolic processes in the body. It plays a role in filtering the blood and also produces the proteins that are required for blood clotting.

Complete answer
Proteins are made up of many different amino acids linked together. Our body requires proteins for the growth and maintenance of our cells and tissues.

In the given options,
>The pancreas is the organ that produces enzymes required for the breakdown of proteins. It also produces insulin, the hormone that controls blood glucose levels. The bone marrow is the tissue present inside the bones that produces new blood cells. The spleen is an organ that filters blood. It recognizes and removes old, malformed, or damaged red blood cells.
>Most of the proteins involved in blood clotting are produced by the liver. Prothrombin is a component of blood which helps in blood coagulation. It is synthesised primarily by the liver. During blood coagulation, prothrombin is converted to thrombin in the presence of thromboplastin and calcium ion.
>Albumin is a globular protein produced by the liver. Albumin is normally present in the blood in large amounts. It is used for binding hormones, other molecules, and drugs. Also, albumin regulates the movement of water between blood and tissues.
>Fibrinogen is an extracellular protein present in the blood plasmas of all vertebral species in large amounts. It is synthesised by the hepatocytes in the liver. During the formation of blood clots, the fibrinogen molecule is converted into fibrin by thrombin.

So, the correct answer is option D i.e., Liver.

Note: The liver is among the most essential protein-making organs. It produces or converts millions of protein molecules every day. The liver produces hundreds of different proteins that have numerous functions. Some transport minerals and vitamins throughout the body. Some act as catalysts (enzymes) to speed up metabolic reactions. Others control the pattern of all the various activities in a cell.