
What is the largest enzyme in the human body?
Answer
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Hint: Enzymes are catalysts with high proteinaceous compounds. It enhances the reactions which occur in the body during various life processes. The largest protein was discovered in 1977 by Koscak Maruyama and co-workers isolated an elastic protein from muscle fiber called Connection (titin).
Complete answer:
INTRODUCTION :
The human body is composed of different types of Enzymes with different functions.Enzyme are the biological polymers that catalyse the biochemical reactions. They are a linear chain of amino acids;the sequence of amino acids specifies the structure which in turn identifies the catalytic activity of the enzyme.
The largest Enzyme in the human body is Titin. The length of titin enzyme is about 27,000 to 35,000 amino acids. Titin is referred to as Connection, which is encoded by TTN Genes. TTN Genes provides instructions for making very large proteins. Titin is a giant protein, greater than 1µm in length, that functions as a molecular spring which is responsible for the passive elasticity of muscle.
Titin is a filamentous protein located in the sarcomere of striated muscle. This protein is responsible for movement of body muscles (skeletal muscles) and heart cardiac muscles. The enzyme Titin is composed of two domains similar to immunoglobulins, and fibronectin. Within the muscle cells the essential component called sarcomere is present. It is the basic unit for muscle contraction, they are made of proteins that generate the mechanical force needed for muscles to contract.
Note :
Titin enzyme has several functions within the sarcomere. The enzyme's main job is to provide structure, stability and flexibility. Titin interacts with the muscle proteins (actin, myosin) for contraction and relaxation.
Complete answer:
INTRODUCTION :
The human body is composed of different types of Enzymes with different functions.Enzyme are the biological polymers that catalyse the biochemical reactions. They are a linear chain of amino acids;the sequence of amino acids specifies the structure which in turn identifies the catalytic activity of the enzyme.
The largest Enzyme in the human body is Titin. The length of titin enzyme is about 27,000 to 35,000 amino acids. Titin is referred to as Connection, which is encoded by TTN Genes. TTN Genes provides instructions for making very large proteins. Titin is a giant protein, greater than 1µm in length, that functions as a molecular spring which is responsible for the passive elasticity of muscle.
Titin is a filamentous protein located in the sarcomere of striated muscle. This protein is responsible for movement of body muscles (skeletal muscles) and heart cardiac muscles. The enzyme Titin is composed of two domains similar to immunoglobulins, and fibronectin. Within the muscle cells the essential component called sarcomere is present. It is the basic unit for muscle contraction, they are made of proteins that generate the mechanical force needed for muscles to contract.
Note :
Titin enzyme has several functions within the sarcomere. The enzyme's main job is to provide structure, stability and flexibility. Titin interacts with the muscle proteins (actin, myosin) for contraction and relaxation.
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