Question

Inflammation of joints due to the accumulation of uric acid crystals is called
A. Gout
B. Myasthenia gravis
C. Osteoporosis
D. Osteomalacia

Answer 1

Hint: Myasthenia gravis, osteoporosis, osteomalacia, and gout all are disorders of the muscular and skeletal system. Myasthenia gravis is a disorder related to the muscular system while the other three are disorders related to the skeletal system.

Complete answer: Gout is a disease related to inflammation of joints. It is a type of arthritis in which accumulation of uric acid crystals occurs in joints. Uric acid forms in excess in the body and then this formed uric acid gets deposited in the synovial joints. A synovial joint is also known as free movable joints or diarthrosis joints. This is a special type of joint covered by a membrane known as the synovial membrane and inside this membrane synovial cavity is present. This cavity is filled with synovial fluid and in this fluid, the accumulation of uric acid crystals occurs. These uric acid crystals deposit in the form of monosodium salts, this excess secretion of uric acid is due to an error in uric acid metabolism.
-Myasthenia gravis is an autoimmune disorder. In this situation, the antibodies from a person’s body attack on self-body cells i.e. antibodies are unable to distinguish between self and non-self molecules. In Myasthenia gravis, the antibodies attack the acetylcholine receptors present on the sarcolemma. Due to this destruction of the receptor takes place and acetylcholine is unable to bind to the receptors. This will result in the weakening of skeletal muscle.
-In osteoporosis, the patient loses his minerals and fibers from the matrix of the bone. Due to this loss decrease in the bone mass occurs and finally, the weakening of the bones takes place. This is an age-related disorder and many factors are responsible for it. The females are more prone to this disease. Because after menopause menstrual cycle in females stops and due to this in the female body the amount of estrogen is decreased.
So, from the above information the correct answer to the given question is option A., i.e., Gout

Note: Due to a decrease in estrogen the osteoclast cells get activated, and osteoclast cells are also known as bone-eating cells. As the mass of bone decreases the bones become more susceptible to fractures.