Question

In mammals, trypsin enzyme is formed from the
A.Trypsinogen by the action of enterokinase
B. Trypsinogen by the action of protein
C. Trypsinogen by the action of fat
D. Trypsinogen by the action of HCl

Answer 1

Hint: Pancreas secretes an inactive proenzyme called trypsinogen. This enzyme reaches the small intestine. An enzyme called as enteropeptidase present in the small intestine which is secreted from intestinal cells, converts trypsinogen to active trypsin enzyme.

Complete answer:
In this question, we have asked about trypsin enzymes. Trypsin is an enzyme that helps us digest protein. We can also call it a proteolytic enzyme or proteinase. As we already mentioned Pancreas secretes an inactive proenzyme called trypsinogen. The trypsinogen then enters the small intestine through the common bile duct. Small intestine secrete an enzyme named enterokinase. This enterokinase breaks down trypsinogen and converts it into its active form trypsin. This active trypsin acts with the other two principal digestive protinases — pepsin and chymotrypsin — to break down dietary protein into peptides and amino acids. They act on semi-digested protein from the stomach and break down this protein into peptides. So, we can say that in mammals, trypsin enzymes are formed from the trypsinogen by the action of enterokinase in the small intestine.

So, the correct option is A.Trypsinogen by the action of enterokinase.

Note:
If trypsin enzymes activate from proteolytic cleavage of trypsinogen in the pancreas, then it can lead to a series of events that cause pancreatic self-digestion which means the enzyme trypsin will digest pancreas, which resulting in pancreatitis.