Question

Gigantism and acromegaly are due to
(a) Hypothyroidism
(b) Hyperthyroidism
(c) Hypopituitarism
(d) Hyperpituitarism

Answer 1

Hint: Gigantism and acromegaly are due to excess secretion of hormones in the master gland that regulates the activity of other endocrine glands. For the treatment of these conditions, strong suppressors are preferred.

Complete step by step answer:
The anterior pituitary secretes growth hormone. Often, it is known as somatotropin. Growth hormone hypersecretion produces gigantism in children and acromegaly in adults. A tumor in the thyroid is responsible for the hypersecretion of growth hormone in the pituitary gland (hyperpituitarism) .
Acromegaly has many unusual signs, including hand and foot enlargement, joint pain, tighter skin, deepening of the voice, headaches, and vision issues.
Excessive growth of bones and enlargement of internal organs is caused by gigantism. Gigantism contributes to severe linear development, headaches, etc.

So, the correct answer is, ‘(c) Hyperpituitarism’.

Additional information:
Pituitary gigantism is a disorder that develops before the epiphyses are closed as growth hormone hypersecretion starts in childhood. There is increased skeletal development and stature, but little bony deformity exists. Growth hormone hypersecretion typically begins in acromegaly between the ages of 20 and 40 years. As growth hormone hypersecretion starts after epiphyseal closure, coarsening of the facial features and soft tissue swelling of the hands and feet are the earliest clinical manifestations.
The thyroid gland is located in the neck between the trachea and larynx and secretes thyroxine hormone, which increases metabolically active tissue oxygen intake.

Note: The pituitary gland is responsible for human growth hormone production, which induces growth and height increase. There is excessive growth hormone development when there is some defect in the pituitary gland that results in gigantism when impaired in childhood and acromegaly in adulthood.