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What is ESRD? What are the symptoms?

Answer
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Hint: Each of the kidneys is about the size of a fist. They're slightly below the rib cage, around the middle of your back. There are around a million microscopic structures called nephrons inside each kidney. Your blood is filtered by them. Wastes and excess water are removed, resulting in urine. Urine travels through tubes known as ureters. It travels to your bladder, where it is stored until you need to urinate.

Complete answer:
ESRD is End stage renal disease
When chronic kidney disease – the slow loss of kidney function — reaches an advanced stage, end-stage renal disease, also known as end-stage kidney disease, occurs. Your kidneys can no longer function properly to support your body's needs if you have end-stage renal disease. The kidneys filter wastes and excess fluids from the bloodstream, which are then expelled in urine. When the kidneys lose their ability to filter, harmful quantities of fluid, electrolytes, and toxins can accumulate in the body.
You may have no indications or symptoms early on in chronic renal disease. As chronic kidney disease progresses to end-stage renal disease, the following signs and symptoms may manifest Vomiting, nausea, Appetite loss, fatigue and weakness sleeping difficulties.
Changes in how much you urinate, decreased mental sharpness, Muscle twitches and cramps, swelling of feet and ankles, Persistent itching, Chest pain, Shortness of breath (if fluid builds up in the lungs), High blood pressure (hypertension).

Note:
The nephrons are the target of the majority of kidney disorders. The kidneys may be unable to eliminate waste as a result of this injury. Genetic issues, trauma, and medications can all be factors. If you have diabetes, high blood pressure, or a close relative with kidney disease, you're more likely to get renal disease. Chronic renal disease wreaks havoc on the nephrons over time. Other issues with the kidneys include: stones, cysts, infections, cancer.
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