
Current commercial method for producing ibuprofen is a stunning application of Green chemistry because ______ .
A.ibuprofen is an anti-inflammatory drug and has various application
B.the previous method required large amounts of solvents and generated large wastes compared to the current method
C.it has very important medicinal value
D.this compound has very less side effects after usage
Answer
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Hint: Ibuprofen is a pain reliever, fever reducer, and inflammation reducer that belongs to the nonsteroidal anti-inflammatory drug (NSAID) family of drugs. Menstrual cramps, migraines, and rheumatoid arthritis are all examples of this. It can also be used to close a preterm baby's patent ductus arteriosus. It can be administered orally or intravenously. It usually starts functioning after an hour.
Complete answer:
In the 1980s, a novel green strategy for Ibuprofen synthesis was devised, requiring just three stages of reactions, a reduced quantity of waste and by-products, just seven intermediate chemicals, the majority of which were reused, and a greater atom efficiency than the traditional technique. The BootsHoechst-Celanese (BHC) Company (United States of America) invented the green pathway, which received the Kirpatrick Chemical Engineering Achievement Award in 1993 and the Presidential Green Chemistry Challenge Award in 1997. The present commercial approach for making ibuprofen is a brilliant example of green chemistry in action. Ibuprofen manufacture using traditional techniques needs six processes, requiring vast volumes of solvents and generating enormous quantities of trash. Ibuprofen synthesis now involves only three stages and produces minimum waste, making it a Green chemical application. During the 1960s, the Boots Group's research unit developed ibuprofen from propionic acid. Isobutyl (ibu), propionic acid (pro), and phenyl are the three functional groups that make up the name (fen). It was discovered as a consequence of research towards a safer alternative to aspirin in the 1950s and 1960s. A team led by Stewart Adams discovered and synthesised the chemical, and a patent application was filed in 1961. Adams first used the medication to help him get over a hangover.
Hence option B is correct.
Note:
Fever (including post-vaccination fever), mild to moderate pain (including pain treatment after surgery), uncomfortable menstruation, osteoarthritis, dental pain, headaches, and discomfort from kidney stones are all common uses for ibuprofen. Around 60% of people respond to any NSAID, and those who don't respond well to one may respond to another.
Complete answer:
In the 1980s, a novel green strategy for Ibuprofen synthesis was devised, requiring just three stages of reactions, a reduced quantity of waste and by-products, just seven intermediate chemicals, the majority of which were reused, and a greater atom efficiency than the traditional technique. The BootsHoechst-Celanese (BHC) Company (United States of America) invented the green pathway, which received the Kirpatrick Chemical Engineering Achievement Award in 1993 and the Presidential Green Chemistry Challenge Award in 1997. The present commercial approach for making ibuprofen is a brilliant example of green chemistry in action. Ibuprofen manufacture using traditional techniques needs six processes, requiring vast volumes of solvents and generating enormous quantities of trash. Ibuprofen synthesis now involves only three stages and produces minimum waste, making it a Green chemical application. During the 1960s, the Boots Group's research unit developed ibuprofen from propionic acid. Isobutyl (ibu), propionic acid (pro), and phenyl are the three functional groups that make up the name (fen). It was discovered as a consequence of research towards a safer alternative to aspirin in the 1950s and 1960s. A team led by Stewart Adams discovered and synthesised the chemical, and a patent application was filed in 1961. Adams first used the medication to help him get over a hangover.
Hence option B is correct.
Note:
Fever (including post-vaccination fever), mild to moderate pain (including pain treatment after surgery), uncomfortable menstruation, osteoarthritis, dental pain, headaches, and discomfort from kidney stones are all common uses for ibuprofen. Around 60% of people respond to any NSAID, and those who don't respond well to one may respond to another.
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