Question

Cortisone hormone is secreted by
(a)Medulla of adrenal
(b)Cortex of adrenal
(c)Pancreas
(d)Thyroid

Answer 1

Hint: Cortisone is a steroid hormone that is a part of the corticosteroids group of hormones. These have an important role in the treatment of inflammatory causes and suppression of immune response during certain processes like an organ transplant.

Complete answer:
The Cortisone hormone is secreted by the adrenal cortex which is a pregnane steroid hormone. Structurally it is related to cortisol and is used to treat animals intravenously, orally, intra-articularly, or transcutaneously to reduce inflammation and attendant pain and swelling in case of injury.

Additional Information:
Cortisone is a corticosteroid and along with epinephrine, is released by the body as a response to stress. Together they increase blood pressure and give the preparation of fight to the body. Cortisone has an important role in the therapeutic field as its injection can reduce inflammation of injury sites like joint, tendon, or bursa and can be used to suppress the immune response in a person with the disease called autoimmune disease. This suppression of the immune system phenomenon can also be used to prevent transplant rejection during organ transplants and important in the treatment of inflammatory conditions. Though it has so many uses, excessive use of this hormone can have side effects like asthma, hyperglycemia, diabetes, anxiety, depression, cataracts, etc.
Corticosteroids are the hormones secreted mainly by the adrenal cortex of vertebrates which include cortisol, cortisone, corticosterone, etc. There are two types of corticosteroids and cortisone is a part of the glucocorticoids. These steroids have anti-inflammatory, immunosuppressive, anti-proliferative, and vasoconstrictive values. The other type is mineralocorticoid which contains Aldosterone. These are involved in the regulation of electrolyte as well as water balance. It is carried out by modulating ion transport in the epithelial cells of the renal tubules of the kidney.
So, the correct answer is the “cortex of adrenal”.

Note: Cortisone along with cortisol is produced as the end product of steroidogenesis. The beginning of this process is marked by the synthesis of cholesterol and proceeds through a series of modifications in the adrenal gland. At first, cortisol is released and later it turns to cortisone in the peripheral tissue in presence of enzyme 11-beta-steroid dehydrogenase.