Question

Christmas disease is another name of
A. Sleeping sickness
B. Down's syndrome
C. Haemophilia-B
D. Hepatitis

Answer 1

Hint: Christmas disease is caused due to deficiency of blood clotting factor or is caused by a mutation of the factor IX gene. It was named after Stephen Christmas as he was the first one to be encountered by this disease.

Complete step by step answer: Let’s us look at all the options to get the correct answer,
Option A, sleeping sickness: Sleeping sickness is another name for human African trypanosomiasis which is caused by an infectious parasite named Trypanosoma brucei, commonly called tsetse fly. Hence, this option is incorrect.
Option B, Down's syndrome: Down's syndrome is another name for trisomy 21 which is a genetic disorder which is caused due to abnormal cell division resulting in an extra copy of the 21st chromosome. Hence, the second option is also incorrect.
Option C, Haemophilia B: Christmas disease also known as Royal disease is another name for Hemophilia B which is caused due to deficiency of blood clotting factor IX. In this disease, blood cannot clot. Thus, this is the correct option.
Option D, Hepatitis: Hepatitis has 5 types and is caused due to swelling or inflammation of the liver. Hence, this is also an incorrect option.
So, the correct option is option C which is Haemophilia-B.

Note: There are three stages of hemophilia. They are as follows-
-Mild Haemophilia B which has factor levels about \[6-30%\] occurs in approx. \[25%\] of patients. It is seen they mostly have bleeding after a serious trauma or surgery, also they might suffer from menorrhagia or postpartum bleeding.
-Moderate Haemophilia B which has the factor levels of about \[1-5%\]. Moderate hemophilia is seen in \[15%\] of patients. They have bleeding direct after injuries and spontaneous bleeding might be seen.
-Severe Haemophilia B is rarely seen and has factor levels of \[<\text{ }1%\]. It is seen to occur in about \[60%\] of patients and has spontaneous bleeding very often into the muscles and joints.