Question

Assertion: Liver is the largest gland of the body. The hepatic lobules are structural and functional units of liver containing hepatic cells arranged in the form of cords.
Reason: Each lobule of liver is covered by a thin connective tissue sheath called Glisson’s capsule.The bile is secreted by hepatic cells.
A. Both assertion and reason are correct and reason is the correct explanation for assertion.
B. Both assertion and reason are correct but reason is not the correct explanation of assertion.
C. Assertion is correct but reason is incorrect.
D. Assertion and reason are incorrect.

Answer 1

Hint: Liver lobules, or hepatic lobules, are small liver divisions described on a microscopic scale. The hepatic lobule is a liver tissue building block consisting of a portal triad of hepatocytes organised between a capillary network and a central vein in linear cords.

Complete Answer:
- As a hexagon-like shape, the hepatic lobule is observed where the central vein is situated at the middle and the hepatocytes form radiating cords from the central vein, similar to the wheel spokes that radiate from the central core. Portal triads are at the external "corners" of the hexagon.
- Portal, midzonal and centrilobular comprise the hepatocellular regions within the classical lobule. Portal hepatocytes, for instance, are those nearest to the portal triads, and the central vein is surrounded by centrilobular hepatocytes.
- Glisson's capsule: The liver capsule. A layer of liver-surrounding connective tissue that ensheaths the hepatic artery, portal vein, and bile ducts within the liver.
- Blood enters the liver lobules through the hepatic artery and then forms hepatic sinusoids that drain into the central vein in the centrilobular region of the liver (also known as zone 3). - An alternative source of blood is the portal vein, carrying nutrient- and antigen-rich blood to the liver from the gastrointestinal system. This blood supply in the sinusoids mingles with that of the hepatic artery.
- The hepatic lobular architecture is identical among species with reticulin and countercurrent bile flow stromal support relative to blood flow. Human hepatic portal structures as well as thin reticular fibres (consisting of type III collagen), which form a loose sinusoid-supporting network, support a greater amount of collagen. Because of their scale and related connective tissue, portal regions in the human liver are often readily visible at low magnification.

The correct Answer is option (A) Both assertion and reason are correct and reason is the correct explanation for assertion.

Note: In the sense that it collects more venous blood than arterial blood, the liver is a special organ, and this is because the liver helps cleanse the blood by detoxification.