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A significant cause of ‘adrenal virilism' is :
A. Hyposecretion of adreno-cortical androgens
B. Hypersecretion of adreno-medullary androgens
C. Hyposecretion of adreno-medullary androgens
D. Hypersecretion of adreno-cortical androgens

Answer
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Hint: Adrenal virilism is a kind of disease in which the extra amount of androgens causes the virilization which further causes the adrenal tumors.

Complete answer:
The excessive amount of secretion of androgen cortisol and corticosteroids causes malignant adrenal tumors when there will be the secretion of cortisol in a huge amount it will result in some other syndrome which also causes hypertension.
The adrenal hyperplasia is known to be a congenital disease which is a kind of denied hyperplasia. Adrenal in which religion is a result of a mutation in which certain enzymes get muted which are responsible for making some steroid bodies. It is the cause of some genetic problems which have led to enzyme deficiency.
It might also happen that the virilism is caused due to the tumor being present in the female’s ovary during the pregnancy. If there is any newborn girl we can see her sex organs as mixed female and male sex organs.
The children who have this kind of disease start growing so fast which is very abnormal and after sometimes their growth gets retarded and stopped. Females with adrenal virilization may have ingrown facial hairs and do not have their Menstruation cycle and so masculine characters and their voice is also so heavy and they grow Adam’s Apple too.

So, the correct answer is A.

Note: Prednisone on drugs is given to the patients who are suffering from this kind of disease and may also require surgery.