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A person buys twelve packets of VANISH detergent. Each packet contains one coupon which bears one of the letters of the word VANISH. If he shows all the letters of the VANISH, he gets one free packet(without a coupon). If he gets exactly one free packet then the number of different possible combinations of the coupons is 
A) 11C5        
B) 461          
C) 17C5             
D) 462

Answer
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Hint: The objective is to find the chances to get the detergent packets consists the  letters V,A,N,I,S,H  out of  twelve detergent packets  because if he shows all the six letters he get a free packet. To get only one free packet, the word “VANISH” should be formed only once. We assign this as VANISH______ . On the remaining blanks we have to do combinations.

Complete step-by-step answer:
It is given that a person buys twelve packets of VANISH detergent . Each packet contains one coupon which bears  one of the letters of the word VANISH. He gets a detergent packet if he shows all the letters of the given word.
Now , we have to solve that if he gets one free  packet  then the number of different possible combinations of coupons.
We have 12  packets and each packet has a coupon which means we get 12 coupons. 
On each coupon, we get V,A,N,I,S,H. But to get one free packet we get  V,A,N,I,S,H words completely once in 6 packets. And in the remaining 6 packets we can get any coupons except the exact letters V,A,N,I,S,H because if we get these letters again, the person will get two extra packets freely which is not asked in the question.
VANISH______
Each of the twelve blanks have six options of letters V,A,N,I,S,H
Let x1,x2,x3,x4,x5,x6 denotes number of times the individual letters V,A,N,I,S,H appear on the coupons.
We write it as x1+x2+x3+x4+x5+x6=12(1) 

Where , 1x1,x2,x3,x4,x5,x612
The required number of combinations of coupons is equivalent to the number of positive integral solutions of equation 1
Now  x1+x2+x3+x4+x5+x6=n
We use the formula n1Cr1 
Apply this formula in equation (1) , we get 
121C61=11C5=462
Now we are going to subtract 1 from the above result as V,A,N,I,S,H combination of letters is also a possibility to occur again but only once it is required.
=4621
=461
If the person gets exactly one free packet then the number of different possible combinations of the coupons is 461. Thus , option (B) is correct.

Note: We use the formula n1Cr(1) . This formula is applied when we have to find the number of non negative integral solutions of the equation. This equation is represented as  x1+x2+x3+...+xr=n where r is the number of variables and n is the sum of all these variables. 
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